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Urgent Cardiac Surgery in a Patient with a Remote History of Heparin-Induced Thrombocytopenia: Use of the Anti-PF4/Heparin ELISA Confirmatory Test
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Urgent Cardiac Surgery in a Patient with a Remote History of Heparin-Induced Thrombocytopenia: Use of the Anti-PF4/Heparin ELISA Confirmatory Test
Urgent Cardiac Surgery in a Patient with a Remote History of Heparin-Induced Thrombocytopenia: Use of the Anti-PF4/Heparin ELISA Confirmatory Test
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The use of established heparin protocols when heparin-induced thrombocytopenia (HIT) antibodies are negative is currently recommended for the management of patients with previous HIT who require cardiac surgery. Routine preoperative testing for HIT antibodies using an anti-PF4/heparin enzyme-linked immunosorbent assay (ELISA) introduces the problem of detecting nonpathogenic HIT antibodies, which can lead to a false diagnosis of the presence of platelet-activating antibodies. Our case report demonstrates the clinical utility of a newer confirmatory procedure performed using high dose heparin. We use this procedure in situations in which pretest probability is low (remote HIT) and the anti-PF4/heparin ELISA test results are weak to moderately positive (absorbance 0.4-1.0).
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Other Articles:
| • | Health/Science Calendar |
| MONDAY, NOV. 12 Infectious cancers Harvard Medical School students continue their "Science in the News" seminar with a lecture about contagious cancers. At 6 p.m. in the Mildred Avenue Community Center in Mattapan. Repeated Wednesday at 7 p.m. in the Armenise Amphitheater at the medical school. Tuesday, Nov. 13 Green history The Massachusetts Historical Society will sponsor a discussion about ... | |
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| • | Impact of Sugar Beet Cyst Nematode, Heterodera schachtii, on Some Physiological Aspects of Two Sugar Beet Cultivars, Nemakill and 7233, in the Rhizosphere Condition |
| The impact of beet cyst nematodes, Heterodera schachtii, on some physiological aspects including proline, potassium and sodium in two sugar beet cultivars, a susceptible 7233 and a resistance Nemakill was evaluated in the rhizosphere condition. In this study a bioassay was conducted with sugar beet seedlings in the presence of different populations of the beet cyst nematodes, 0, 10, 20 juveniles 1-1 g. soil as a biostressor in glass tubes (20x3 cm Ø) in growth chamber, totally 36 tubes. The tubes were placed in a growth chamber with 16-h artificial light, eight fluorescent 40 watts, at 25 and 21°C at darkness and moistened regularly with a half Hoagland`s nutrient solution. The proline, potassium and sodium changes of treated and untreated plants were measured 45 days after nematodes` inoculation. In this stage, the root of plant was freed from soil and debrises by a fine jet of water stream and the number of developed females of nematodes counted on the root surface and recorded. Results of this study revealed that the proline in leaves, sodium in leaves and roots as well as potassium in roots were increased but K+ decreased in leaves in both cultivars as the population of nematodes increased in the soil. Results of this study indicated that a few number of nematodes` females was developed on Nemakill`s roots in comparison with the other treated and untreated susceptible cultivar in the rhizosphere condition. | |
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| • | nanotechnology, nano technology, nanoscience, nanotech, molecular nanotechnology, nanomaterials |
| We define nanoscience as the study of phenomena and manipulation of materials at atomic, molecular and macromolecular scales, where properties differ significantly from those at a larger scale; and nanotechnologies as the design, characterisation, production and application of structures. | |
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| • | Study helps pinpoint genetic variations in European Americans |
| Troy, N.Y. An international team of researchers has identified just 200 positions within the curves of the DNA helix that they believe capture much of the genetic diversity in European Americans, a population with one of the most diverse and complex historic origins on Earth. Their findings narrow the search for the elusive ancestral clues known as single nucleotide polymorphisms, or SNPs, th... | |
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| • | meade.com - Meade Telescopes, Microscopes, Meade Instruments, Telescopes by Meade |
| astronomers, astronomy, astrophotography, binoculars, comets, constellations, coronado, digital camera binoculars, galaxies, mars the planet, mead, mead telescopes, meade, meade instruments, meade telescopes, microscopes, moons, optics, planets, redfield optics, simmons optics, solar systems, stars, telescopes, weaver optics | |
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| • | Confessions of an Alien Hunter by Seth Shostak |
Confessions of an Alien Hunter A Scientist's Search for Extraterrestrial IntelligenceHardcover, 320 pages | National Geographic | Biography & Autobiography; Science - Astronomy; Biography & Autobiography - Science & Technology | $27.00 | March 17, 2009 | 978-1-4262-0392-3 (1-4262-0392-6) |
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Anesthesia & Analgesia
By editor@weddingssitereviews.com - Copyright 2007. Bio-Medicine All Rights Reserved. - version: v1.5 build A
By editor@weddingssitereviews.com - Copyright 2007. Bio-Medicine All Rights Reserved. - version: v1.5 build A